http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-499044-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e00a330ce4c1e74ccd312f4e40e9ac81 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-26 |
filingDate | 1937-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1939-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-499044-A |
titleOfInvention | Process for the manufacture of metallic iron for use as a pharmaceutical preparation |
abstract | Metallic iron powder for medical use is rendered more readily soluble in the gastric juices by bringing the particles into permanent contact with small proportions of platinum ruthenium, osmium, iridium or rhodium by depositing such metal by reduction on the metallic iron powder, or by reducing a compound of the metal simultaneously with a compound of iron. The specified metals have a lower hydrogen over-voltage than that of iron so that polarization by the hydrogen evolved on solution is reduced, and the iron dissolves more quickly and completely. The second metal is used in proportions of 0,1 to 1 per cent and is insufficient to form a complete coating on the iron particles. The powder may be made up in the form of tablets by coating with digestible material such as chocolate and malt, or doses of the powder may be provided with an air- and water-tight coating of an alcoholic solution of vegetable resins. According to examples: (1) reduced iron powder is added to an aqueous solution of platinic chloride, through which carbonic acid is passed, so that the platinium is deposited on the iron; (2) an acid solution of ferrous sulphate is mixed with a solution of platinum chloride, caustic soda is added, and the precipitate obtained is washed, dried, pulverized and reduced by heating in a current of hydrogen. Specification 386,499, [Group II], is referred to.ALSO:Metallic iron powder for medical use is rendered more readily soluble in the gastric juices by bringing the particles into permanent contact with small proportions of platinum, ruthenium, osmium, iridium or rhodium by depositing such metal by reduction on the metallic iron powder, or by reducing a compound of the metal simultaneously with a compound of iron. The specified metals have a lower hydrogen over-voltage than that of iron so that polarization by the hydrogen evolved on solution is reduced, and the iron dissolves more quickly and completely. The second metal is used in proportions of 0,1 to 1 per cent and is insufficient to form a complete coating on the iron particles. According to examples: (1) reduced iron powder is added to an aqueous solution of platinic chloride, through which carbonic acid is passed, so that the platinum is deposited on the iron; (2) an acid solution of ferrous sulphate is mixed with a solution of platinum chloride, caustic soda is added, and the precipitate obtained is washed, dried, pulverized and reduced to the metallic state by heating in a current of hydrogen. Specification 386,499 is referred to. |
priorityDate | 1937-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.