http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-456916-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43d319a54ca3f697e914f4af7a0a3f7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_048df2db116fb27c0fc7ec8c939abffe http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0964419038d49d5c55eb90ad489dcd7e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-08 |
| filingDate | 1935-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1936-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-456916-A |
| titleOfInvention | Improvements in and relating to the manufacture of substituted diamines |
| abstract | Diamines of the formula R1R2N(CH2)n NR3R4, where " n " is an integer from 7 to 13 inclusive and R1, R2, R3 and R4 are the same or different alkyl groups or R1R2 and/or R3R4 represent the pentamethylene chain, are made by heating together an aminoalkyl halide of the formula R1R2N(CH2)nX, where X denotes a halogen atom and a secondary amine NHR3R4. The halogen salt of the aminoalkyl halide may replace the aminoalkyl halide itself. The products are useful as amoebicides. In examples, K-chloro-n-decyldi-n-amylamine is heated with (1) di-n-butylamine and (2) piperidine; di-n-amylamine is reacted with (3) K-chloro-n-decyl-di-n-butylamine, (4) K-bromo-n-undecyl-di-n-amylamine hydrobromide, (5) lambda-chloro-n-undecyl-di-n amylamine hydrochloride or lambda-bromo n-undecyl-di-n-amylamine hydrobromide; (6) lambda-bromo-n-undecyl-di-n-butylamine hydrobromide is heated with di-n-butylamine. The above aminoalkyl halides are prepared by the process of Specification 402,159, or by boiling the appropriate aminoalcohol with concentrated hydrobromic acid. In the examples, lambda-chloro-n-undecyl-di-n-amylamine hydrochloride is prepared by treating lambda-di-n-amylamino-n-undecyl alcohol with thionyl chloride in chloroform solution below 0 DEG C., and lambda-bromo-n-undecyl-di-n-amylamine hydrobromide is prepared from the same aminoalcohol by boiling with hydrobromic acid. lambda - Bromo - n - undecyl - di - n - butylamine hydrobromide is prepared from lambda-di-n-butylamino-n-undecyl alcohol. Secondary amines of the above formula are obtained by hydrolysis of the corresponding p-toluenesulphonamides, which are made by treating the sodium salt of p-toluenesulphonamide successively with the appropriate alkyl bromides, chlorides, or toluene-sulphonates. |
| priorityDate | 1935-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.