http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-435195-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b04f5b6a02051c94d6eaf190b751ed2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
filingDate | 1934-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1935-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-435195-A |
titleOfInvention | Manufacture of preparations of hormones |
abstract | Stable solid mixtures of hormones with diluents are prepared by dissolving the hormone together with an albumen or an albumen decomposition product of high molecular weight in a solvent for both constituents and then adding a precipitant for the two substances. The mixed precipitate is dried and may be further diluted with an excipient such as urea or lactose. According to examples (1) posterior hypophysis hormone and sodium salt of protalbinic acid are dissolved in glacial acetic acid and precipitated with a mixture of acetone and ether, (2) posterior hypophysis hormone dissolved in water is mixed with normal serum and the hormone and serum albumen precipitated with a mixture of alcohol and ether, (3) posterior hypophysis hormone and gelatine are precipitated from glacial acetic acid by means of ether, (4) insulin and gelatin are precipitated from glacial acetic acid by means of ether, (5) the sexual hormone of the anterior hypophysis obtained from urine is dissolved in water, mixed with normal serum and precipitated with alcohol and ether. Casein and the sodium salt of lysalbinic acid may also be used as diluents. The previous use, in the form of snuff, of the dried whole posterior lobe of the hypophysis, or of the hormone of this gland diluted only with inert powders such as urea or lactose is referred to. |
priorityDate | 1933-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.