http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-409131-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6108c9a7f7a472c2db8923daca0ec8d6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C37-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C37-18 |
| filingDate | 1933-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1934-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-409131-A |
| titleOfInvention | Method of carrying out the friedel-crafts reaction |
| abstract | Aliphatic groups (including acidyl groups and aralkyl groups) are introduced into the nuclei of organic compounds having an aromatic nucleus by reacting the said compounds with a halide of the aliphatic group in the presence of hydrated ferric chloride. Suitable aromatic compounds are aromatic hydrocarbons, e.g. benzene, toluene, xylene and naphthalene, and their nuclear substitution products, e.g. amino, halogen (e.g. chloro) or carboxylic derivatives, and particularly aromatic compounds having nuclear hydroxy groups such as phenols, e.g. phenol or cresols, and naphthols. Suitable aliphatic halides are halogenated aliphatic hydrocarbons, e.g. methyl, ethyl, propyl, butyl and amyl chlorides, bromides or iodides, benzyl chloride, vinyl chloride, methylene chloride and chloroform, and acid chlorides, e.g. acetyl chloride. The reaction of vinyl halides with aromatic hydroxy compounds, however, is disclaimed. The reaction may be carried out by heating the reagents and catalyst together under reflux, or by heating the ferric chloride with the aromatic compound and slowly running in the aliphatic halide. In examples: (1) phenol, tertiary butyl chloride and hydrated ferric chloride are heated to 80--90 DEG C. and the reaction mixture is poured into water whereby crystals of tertiary butyl phenol separate; (2) the tertiary butyl chloride is replaced by tertiary amyl chloride, yielding tertiary amyl phenol. Specification 409,132 is referred to. |
| priorityDate | 1932-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.