http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-308600-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8cd3130766f603080ef732946d3da27 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685 |
| filingDate | 1929-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1930-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-308600-A |
| titleOfInvention | A process for increasing the therapeutic action and lowering the toxicity of arsenic-containing organic therapeutic substances |
| abstract | 308,600. Steinfeld, J. I. March 24, 1928, [Convention date]. Medicinal preparations. - Therapeutic compounds are obtained by reaction between an aromatic organo - arsenic compound having therapeutic properties and a phosphatide or cerebroside or a phosphatide-containing extract or suspension of an animal organ. Organic compounds specified are-the sodium salt of p-aminophenylarsinic acid, p-dioxy-m-diamino-arsenobenzenedibydrochloride, the sodium salt of pdioxy - m - diaminoarsemobenzene - m - monomethanesulphinic acid, and the sodium salt of p - - dioxy - m - diamino-arsenobenzenedimethanesulphonic acid. Phosphatide materials referred to are lecithin, kephalin, and extracts or suspensions of brain, liver, or kidney. According to an example ox brain is passed through a sieve, suspended in physiological salt solution, sterilized by heating and centrifuged. The sediment is taken up in salt solution, agitated for an hour with a solution of the sodium salt of dioxy - diaminoarsenobenzene - monomethanesulphinic acid, and repeatedly washed in salt solution and centrifuged until the washing solution no longer containsappreciable quatities of arsenic. The final sediment is taken up in physiological salt solution and standardized or may be dried. The product is stated to be stable in contact with air. The Specification as open to inspection under Sect. 91 (3) (a) relates also to the preparation of compounds of lipoids with organic metal compounds in general and refers to the di-sodium salt of 4-sulphomethylamino - 2 - auromercaptobenzene-1-sulphonic acid as an additional example of such metal compounds. This subject-matter does not appear in the Specification as accepted. |
| priorityDate | 1928-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.