| abstract |
A nutritional supplement for use by oral administration to a human for ameliorating adverse medical conditions deriving at least in part from metabolic and/or intestinal dysfunction, wherein the supplement comprises a mixture of bioflavonoids which include at least 45% wt/wt of naringin and at least 15% wt/wt of neohesperidin of the bioflavonoids present. Preferably the mixture of bioflavonoids is derived from the pith of immature bitter oranges. The adverse medical condition is preferably a gastrointestinal or metabolic condition selected from an insulin resistance syndrome condition, for example, type 2 diabetes or prediabetes, dyslipidaemia, gastrointestinal ulcer, irritable bowel syndrome or leaky gut syndrome, duodenal ulcer, central adiposity, hypertension, or non-alcoholic fatty liver disease. Preferably the oral administration comprises 100mg-5g/day. |