http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2593742-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcba01eaf7ccdd7e7fe91bbf8cd19702 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 |
| filingDate | 2020-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e83372d98d7dea384de99cf72a8780 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73aadb5e4f58335006566262c9297a5a |
| publicationDate | 2021-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2593742-A |
| titleOfInvention | Coronavirus |
| abstract | Surfactant protein D (SP-D) or a derivative thereof, is disclosed, but not exemplified, for use in preventing and/or treating a coronavirus infection such as SARS-CoV-2 which has caused one or more of pneumonia, bronchiolitis, bronchitis and severe acute respiratory syndrome (SARS). Preferably, the SP-D fragment has carbohydrate binding activity and comprises an amino acid sequence having at least 70% sequence identity to SEQ ID NO:2 or SEQ ID NO:4 and may be a fusion protein comprising a carbohydrate-binding domain from SP-D fused an anti-inflammatory polypeptide. A composition of SP-D may further comprise Surfactant Protein A (SP-A) or Mannan Binding Lectin (MBL) or an additional anti-viral agent. The composition is further disclosed for use in the treatment of inflammation, testicular dysfunction and pain in a subject infected with a coronavirus. A nucleic acid encoding SP-D for use in treatment and/or prevention of a coronavirus infection in a subject is also disclosed wherein the nucleic acid has at least 70% homology to SEQ ID: NO.1 or NO:3. The use of Surfactant Protein D in an in vitro method of detecting a coronavirus infection is also disclosed but not exemplified. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023281523-A1 |
| priorityDate | 2020-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 328.