Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ebd44e6ae7403d8c6458715a09357b2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-26 |
filingDate |
2019-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f911408de40d7c0cdc2deefa2c35fb97 |
publicationDate |
2021-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
GB-2590601-A |
titleOfInvention |
Method of mass spectrometry |
abstract |
A method of mass spectrometry is provided comprising adding an isotopologue of a target analyte to a sample and ionising the sample and isotopologue as it elutes from a chromatography system to form precursor ions. The precursor ions are mass analysed using a data independent acquisition (DIA) methodology comprising performing mass analysis scans in the MS1 domain and performing mass analysis scans in the MS2 domain. Upon identifying that the isotopologue is eluting from the chromatography system, the method further comprises performing a plurality of target scans each having a target isolation window including a mass to charge ratio representative of the target analyte over the duration of a chromatographic peak of the isotopologue for at least one of identification and quantitation of the target analyte, wherein the target scans are configured to provide additional quantitation data for the target analyte. |
priorityDate |
2019-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |