http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2576886-A
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0b31a7b990af0541dc90d60c613a00e |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-4828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5615 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06T7-00 |
filingDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6ac5eac8f411c36e7d4563aa7ba0877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ad1381669b15cdcd08adf100e0a9ac5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b9ec29e588927844fd3fbc0eb8d3adc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4f7a8175307ec7c389de22e1ad1ed2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc7c853bdde03838fbd52318c97cefd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1550e8ba045378a6f86b40fa6771ae02 |
publicationDate | 2020-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2576886-A |
titleOfInvention | A method of analysing images |
abstract | A method of analyzing the magnitude of Magnetic Resonance Imaging (MRI) data for images acquired at arbitrary echo times for a subject, to determine the relative signal contributions of at least two species to each voxel of the images, the method comprising the steps of: using the magnitude only of the multi-echo MRI data of images from the subject, where the images are acquired at asymmetric echo times; fitting the magnitude of said multi-echo MRI data acquired at asymmetric echo times, to a single signal model to produce a plurality of potential solutions for the relative signal contributions for each of the at least two species from the model, by using a plurality of different starting conditions to generate a particular residual value for each of the plurality of starting conditions, where said residual values are independent of a field map term for the MRI data and analyzing said residual values to calculate the relative signal separation contribution for each species at each voxel of the images. The analysis of residual values may comprise a comparison process wherein the lowest residual value is deemed to be the correct solution for said signal and the fitting process may involve a regularized least squares estimation. The signal model may include a spectral model of one of the at least two species with more than one spectral component and/or it may include at least one relaxation time constant to correct for signal decay. The species signal contribution may be used to generate separate images showing the results for each species or they may be used to estimate a field heterogeneity (“fieldmap”) term. The at least two species may be water, fat, hyperpolarized contrast elements or metabolites of such elements, markers for the presence of cancerous cells. The fitted values of a voxel may be used to update a likelihood map of the presence of at least one species in the voxel. |
priorityDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.