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publicationDate 2018-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2563435-A
titleOfInvention Three-photon light sheet imaging
abstract A light sheet imaging system comprising an illumination arrangement for generating a light sheet (LSG) for three-photon excitation of a fluorescent sample and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam or an Airy beam. The light sheet may use an optical source which is configured to generate a stream of optical pulses. The illumination arrangement may have a pulse compression arrangement for compressing the optical pulses. The light sheet imaging system may use gradient index (GRIN) lenses GRIN1 and GRIN2 (Figure 9) as input and output lenses.
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