http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2493982-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed7919c5019f9a037e4036b8ee0dbe10 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2814 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2011-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_021cc4ec892ed29ecb5744c0da52f0e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2e7355a9694e08b95798ed4b0a13d9e |
| publicationDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2493982-A |
| titleOfInvention | Disease treatments involving histone deacetylases |
| abstract | A cancer, dementia or muscular dystrophy treatment composition comprising an agent capable of (a) inhibiting binding or interaction between a conserved motif (SEQ ID NO:6) of a class I histone deacetylase (HDAC) and its corresponding co-repressor protein; (b) inhibiting binding or interaction between an HDAC and a conserved motif (SEQ ID NO:16) of its corresponding co-repressor protein; (c) inhibiting binding or interaction between an inositol phosphate molecule and either (i) an HDAC or (ii) its corresponding co-repressor protein or (d) inhibiting synthesis of inositol tetraphosphate or its release from intracellular stores and/or increasing degradation of inositol tetraphosphate. Also claimed are methods for diagnosing a subject suffering from a disease characterized by inappropriate histone deacetylation comprising screening for the presence of a mutation in an HDAC or HDAC co-repressor protein. |
| priorityDate | 2011-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 174.