| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a323c8bd87e0ebc7404e9edb57bd315e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96444 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 |
| filingDate |
2010-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4347e66410c55fce637d4b66e8cd072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cd642852bfceec27b7f6deaca4c2d09 |
| publicationDate |
2012-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
GB-2485590-A |
| titleOfInvention |
Method for detecting at least one direct factor Xa inhibitors |
| abstract |
A method for detecting at least one direct factor Xa inhibitor in a sample, which does not contain citrated blood plasma, comprises the steps of: (a) providing a sample containing a factor Xa inhibitor; (b) providing a composition containing factor Xa; (c) providing a composition containing a chromogenic substrate conjugated to a detectable substance; (d) mixing the sample of step (a) with the composition of step (b) and the composition of step (c) under conditions which allow the binding of the at least one direct factor Xa inhibitor to factor Xa and which allow the factor Xa to release the detectable substance from the chromogenic substance; (e) measuring the amount of detectable substance; Preferably, the factor Xa inhibitor is rivaroxaban, the chromogenic substrate is S-2222, and the sample is urine or serum. The method may be provided as part of a point of care test. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019057367-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2818871-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10676731-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10337048-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014207107-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3063170-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3460070-A1 |
| priorityDate |
2010-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |