http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2483393-A

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filingDate 2010-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a84a0ef8f70b264a450c99c3557f4f56
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publicationDate 2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2483393-A
titleOfInvention Signal amplification microspheres, their use in one-step and multi-step analytical amplification procedures and methods for their production
abstract The present invention relates to microspheres comprising protein signal precursor molecules, or a carrier protein bonded to signal precursor molecules, wherein said signal precursor molecules are activatable to generate a detectable signal whilst remaining bonded to the carrier protein. Also disclosed is a method of making such microspheres comprising the steps of mixing protein molecules with a matrix former in solution; adding a reducing reagent to the mixture; removing the reducing reagent; and removing the matrix former to leave microspheres of protein molecules. Also disclosed are bioassay methods using the microspheres to provide signal amplification, including an amplification cycling procedure.
priorityDate 2009-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 32.