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publicationDate 2011-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2476494-A
titleOfInvention Formulation for the sublingual delivery of sufentanil
abstract A pharmaceutical formulation for the sublingual delivery comprises sufentanil (e.g. sufentanil citrate 0.005-0.05%), an alcohol (e.g. ethanol (10-50%)) and water or an aqueous buffer (e.g. citrate). Preferably the formulation comprises the sweetener saccharin (0.3%), menthol (as levomenthol or racementhol at 1%) and is pH8.2. The formation may be loaded onto a canister for sublingual delivery, preferably the canister comprises a single dose delivered by one spray action.
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