abstract |
A dispersion of active-containing microbeads within a non-aqueous continuous phase, the microbeads comprising a plurality of droplets of active within a hybrid matrix. The matrix comprises both a hydrophilic organic material selected from poly(vinyl alcohol), poly(carbohydrates) and poly(alkylene glycols), and an inorganic oxide that forms continuous network through the organic material. Preferably, the organic material is a polyvinyl alcohol (PVOH) having a degree of hydrolysis from 50-99%; cellulose; hydrolysed starch; organic gums; polyethylene glycol. Preferred inorganic materials include silicon alkoxides, optionally partially or totally hydrolysed; inorganic precursors M(OR"')0-4X0-4, wherein M is a metal or metalloid, R"' is a lactate, alkyl or aryl residue and X is an halogen. The continuous phase may contain the same or a different active than the microbeads. The preparation of a microbead active delivery system comprising the dispersion of the invention. The examples relate to dispersions with hybrid matrices made from PVOH Mowiol (RTM) and tetraethoxy silane (TEOS) precursors. Exemplified applications include a shampoo composition comprising perfume microbeads in a continuous phase of the same fragrance; a toothpaste including flavour oil microbeads dispersed in a continuous phase with a different flavour. |