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filingDate 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcbfd35fa9ed04997b060e227888a052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29e584e213911fa1f8452b230e43907e
publicationDate 2010-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2463436-A
titleOfInvention (11C)methoxy-radiolabelled 2,3',4,5'-tetramethylstilbene (TMS) and its preparation and use
abstract This invention pertains generally to the field of radiochemical synthesis, and more specifically to methods of preparing [11C]methoxy-radiolabelled 2,3',4,5' -tetramethoxystilbene (TMS) from an unlabelled hydroxy precursor of 2,3',4,5' -tetramethoxystilbene (TMS) that has a pendant hydroxyl group, by reaction with [11C]methyl trifluoromethanesulfonate (CF3SO2O11CH3), also known as [11C]methyl triflate, or [11C]methyl iodide (11CH3I). This reaction converts the pendant hydroxyl group into a pendant [11C]methoxy group. The resulting [11C]methoxy-radiolabelled product is useful, for example, as an in vivo positron emission tomography (PET) tracer, for example, for tumours (e.g., cancer tumours) and/or beta amyloid plaques (e.g., Alzheimer's disease). The present invention also pertains to the resulting [11C]methoxy radiolabelled products, compositions comprising them, their use in methods of (e.g., PET) imaging, their use in methods of medical treatment and diagnosis, etc.
priorityDate 2007-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 37.