| abstract |
An alternative synthesis of certain 2(S), 4(S), 5(S), 7(S)-2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amide derivatives or pharmaceutically acceptable salts thereof which utilises a palladium coupling reaction as defined in Scheme 1 therein. Novel intermediates are used in the preparation of the above target compound. |