abstract |
A method for testing an agent for its ability to inhibit binding between fibroblast growth factor (FGF) and a heparanase substate comprises bringing the test compound and a labelled heparanase substrate into contact with immobilised FGF on a solid support, and then detecting the presence of the label remote from the solid support. The heparanase substrate ma be fluorescein-labelled heparan sulphate. |