| abstract |
Compounds for use in the treatment of conditions associated with angiogenesis or for diseases associated with cyclooxygenase-2 (COX-2) of the formula: <EMI ID=1.1 HE=36 WI=50 LX=278 LY=762 TI=CF> <PC>wherein when R1 is H or OH, R2 is 3-methylbut-1-enyl, 3-methylbut-2-enyl or similar; and when R1 is OH, R2 is a hydrocarbon chain; and analogues thereof. Thus these compounds may be useful in the treatment of conditions associated with inflammation, angiogenesis and tumour growth. |