| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dea97595058f316a875c28a64efb90da |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-42 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-746
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-76 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-76 |
| filingDate |
2003-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48ed134ae6680cbcf2ddbf58b62a8d77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb65f255017407be62315d595397835c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73c3ef24854e9cae3cb1160537ce51aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_873e508dd6a084033897fd6518168d89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5a38cdb4ea649dbdb55d37f66833338 |
| publicationDate |
2005-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
GB-2404734-A |
| titleOfInvention |
A method of screening a sample for abnormally glycosylated and/or expressed proteins |
| abstract |
A method of screening a sample for one or more abnormally glycosylated and/ or expressed proteins comprising the steps of exposing the sample to two or more different lectins and/or antibodies, determining the extent of binding of the sample to at least two of the lectins and/or antibodies and comparing the extent of binding to at least two lectins/antibodies with that of the control sample. The lectins/antibodies may be immobilised on a solid surface to form an array and the binding of the sample may be performed in real time and be detected by an evanescent optical technique. The method may be used to test body fluids for the presence of recombinant erythropoietin (rEPO), chorionic gonadotrophin, hGH or transferrin to determine use of glycoprotein drugs or diagnose glycosylation disorders. The lectins may be Sambucus nigra agglutinin or Maackia amurensis agglutinin. Kits of parts for use in the methods are disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1366364-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1366364-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021205059-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8759259-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101487844-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9551721-B2 |
| priorityDate |
2003-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |