http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2399218-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0149762ef65f17ca81b0135f4a2170a6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0045 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2004-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcc518aaf4a2821ed6b96d8ff0746a56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71a678e60588ec1cc9cda486043ed75d |
publicationDate | 2004-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2399218-A |
titleOfInvention | Tandem mass spectrometry utilising in-source decay (ISD) |
abstract | The invention relates to the acquisition of mass spectra of biopolymers, especially of proteins, in tandem mass spectrometers with matrix-assisted laser desorption ionization (MALDI), for the examination or determination of terminal sequence patterns. A first generation of fragment or daughter ions of a biopolymer are generated by so called in-source fragmentation/decay (ISF/ISD). Granddaughter ions, obtained by further fragmentation of a selected type of daughter ion, are subsequently detected and measured. The further fragmentation may be by means of collisionally-induced dissociation (CID), surface-induced decomposition (SID), photon-induced dissociation (PID), or metastable decay/laser-induced decomposition (LID). Preferably the tandem mass spectrometer is a tandem time-of-flight mass analyser (TOF/TOF-MS). The invention enables the determination of the terminal sequences which are otherwise difficult to measure. |
priorityDate | 2003-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.