| abstract |
A pharmaceutical composition comprises azelastine or a salt thereof, and a steroid, the composition being in a form suitable for nasal or ocular administration. Preferred steroids include beclomethasone, mometazone, fluticasone, budesonide and cyclosenide and preferred formulations include aerosols, ointments, eye drops, nasal drops or sprays, inhalation solutions or insufflation powders. Also provided is a method of treating irritation or disorders of the nose and eye comprising applying directly to nasal tissues or to the conjunctival sac of the eyes, a medicament which contains a member selected from the group consisting of azelastine and its pharmaceutically acceptable salts, in combination with a steroid. |