http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2386891-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c7b1a8b14f735480e2ac5c6e54c2543 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-86 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
filingDate | 2002-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfaacc1c19fc230007f3dd4d0b694cb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59632fa9691a599adbc3485dceefd1bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94fb2fd7efba19d7200fca7db7e29da2 |
publicationDate | 2003-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2386891-A |
titleOfInvention | Antibacterial benzofuran-2H-3-ones |
abstract | A compound, for therapeutic use, eg. antibacterial, of Formula 1 <EMI ID=1.1 HE=44 WI=62 LX=759 LY=613 TI=CF> R1, R2 are independently selected from the group consisting of hydrogen, C1-6 alkyl, where alkyl may be optionally further substituted with halogen, hydroxy, cyano, trifluoromethyl, -CO2R4, C1-6 alkoxy. R1 and R2 together may also represent a bridging group -(CR4R5)n- where n is one or two and R4 and R5 are as defined below. Ar represents a carbocyclic or heterocyclic, single or fused aromatic ring. This includes benzene, naphthalene and heterocycles containing one or more heteroatoms selected from O, N or S such as pyridine, pyrimidine, furan, oxazole, thiazole, indole acridine and the like. The bond to the Ar group may be from any ring atom. Furthermore, the aromatic ring may be optionally substituted by one or more groups R3 independently chosen from: H, C1-8alkyl, C2-8alkenyl, C1-8alkyl-OH, C1-4alkylaryl, C1-4alkylCO2R4, -CO2R4, -CONR4R5, -CN, -CF3, -SO2R4, phenyl, R1-substituted phenyl, heterocyclyl, halogen, hydroxyl, C1-8alkoxy, arylC1-8alkoxy -NH2, - NHR4,-N(R4)COR5, -NR4R5, NO2 and SR4 Wherein R4 and R5 are independently defined as: H, C1-8alkyl, C2-8alkenyl, C1-4alkylaryl, C1-4alkylCO2R4, aryl or taken together R4 and R5 are -C1-6alkyl- And aryl is defined as: Phenyl, or heterocylyl optionally substituted by C1-4alkyl, -OH, -OCH3, -CO2R4, halogen or -CF3. Independent of use, most of the above compounds are claimed. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111285829-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7148254-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111285829-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106188031-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106188031-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005047275-A1 |
priorityDate | 2002-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 798.