http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2371748-A

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28
filingDate 2000-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b94397f75fea9f4837f0b6d26ec9af9a
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publicationDate 2002-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2371748-A
titleOfInvention HMG-COA reductase inhibitor extended release formulation
abstract Controlled release oral solid dosage form for the reduction of serum cholesterol levels in humans include a drug comprising an alkyl ester of hydroxy substituted naphthalenes (e.g., lovastatin) and a controlled release carrier, such that the dosage form provides a mean time to maximum plasma concentration (T<SB>max</SB>) of the drug which occurs at about 10 to about 32 hours after oral administration on a once-a-day basis to human patients. The dosage form provides a therapeutically effective reduction in serum cholesterol levels. Methods of reducing serum cholesterol levels in humans are also disclosed.
priorityDate 1999-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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