| abstract |
Double stranded RNA (dsRNA), or DNA capable of producing dsRNA, is introduced into a nematode such as <I>C. elegans</I> by feeding thereto either a bacterial cell comprising a suitable expression vector or such an expression vector itself. The expression vector may comprise a promoter or promoters oriented relative to a DNA sequence such that it/ they can initiate transcription thereof to dsRNA upon binding of an appropriate transcription factor to the promoter(s). The DNA sequence may be present in a sense and an antisense orientation relative to the promoter(s). The bacterial cell may be an <I>E. coli</I> cell. |