| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83ebcb287b2343acc6752fb97ce7e806 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-924
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-43534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2000-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_835ead34609cd218f8114f9a70c48406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb6493b76d230ff581d0944baf583472
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a5e4131b8d59e6d09edf1d2a6eb8b6a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52f2847a9a65a2cddec94011f17b8006 |
| publicationDate |
2001-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
GB-2359627-A |
| titleOfInvention |
Screening etc. methods using nematodes |
| abstract |
A method of identifying a mutation which suppresses the phenotype of a nematode worm which is characteristic of the phenotype generated by exposure of a wild-type worm to a chemical comprises (a) subjecting worms to random mutagenesis; (b) dispensing one mutagenised F1 worm into each well of a multi-well assay plate; (c) allowing the worms to generate F2 offspring; (d) contacting the F2 worms with said chemical; (e) identifying worms exhibiting no or only minor changes in phenotypic, physiological, biochemical or behavioural characteristics using non-visual means; and (f) isolating from the identified worms a gene which is mutated to identify said suppressor mutation. Also claimed are methods for identifying genes that modulate the activity of a selected compound which has a defined effect on a nematode and for identifying chemicals which modulate the effect which a first compound has on the phenotype etc. of a nematode. |
| priorityDate |
1999-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |