| abstract |
Polypeptide and polynucleotide sequences encoding rat mdr1a are disclosed. Methods for screening to identify compounds which stimulate or inhibit the function of mdr1a, or which neither stimulate nor inhibit the function of mdr1a are disclosed. An expression system for the expression of mdr1a polypeptide in a compatible host cell, preferably either by transformation or transfection and a process for recovering said polypeptide from a culture of said cells is also disclosed. |