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filingDate 1998-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df0a6c6d57f27e26907479a558b21641
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publicationDate 2000-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2342352-A
titleOfInvention Tramadol salts thereof and process for their preparation
abstract Cis-Tramadol hydrochloride is prepared by forming a Mannich hydrochloride, liberating the Mannich base, reacting the Mannich base with a Grignard reagent to form a base hydrate of cis-Tramadol which is used to form pure cis-Tramadol hydrochloride. Also claimed is the base hydrate of cis-Tramadol per se and its use as a medicament.
priorityDate 1997-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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