http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2340493-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfba2de42c7c8ba3daf49e0fadb8ac6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36bd849a2b3ec868e4955bdc799e6b4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78990be212d8bce4291eac6df0fc8884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-873 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-873 |
| filingDate | 1996-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44c550742f1fdc1fdc089d6586d58980 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ec39e4e347637aef8ef97bfdea9a730 |
| publicationDate | 2000-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2340493-B |
| titleOfInvention | Unactivated oocytes as cytoplast recipients for nuclear transfer |
| abstract | A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division. The oocyte is not activated at the time of transfer, so that the donor nucleus is kept exposed to the recipient cytoplasm for a period of time. The diploid nucleus can be donated by a cell in either the G0 or G1 phase of the cell cycle at the time of transfer. Subsequently, the reconstituted embryo is activated. Correct ploidy is maintained during activation, for example, by incubating the reconstituted embryo in the presence of a microtubule inhibitor much as nocodazole. The reconstituted embryo may then give rise to one or more live animal births. The invention is useful in the production of transgenic animals as well as non-transgenics of high genetic merit. |
| priorityDate | 1995-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.