abstract |
A process for the diagnosis of a cancerous, or pre-cancerous, state in a subject comprises assay of a sample comprising cells (preferably mutant p53 cells), or an extract therefrom, for the co-elevation of CDK1 and CDK4. The assay may be performed by contacting the sample with labelled antibody against CDK1 and/or labelled antibody against CDK4. A kit for performing the diagnosis is described. |