http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2328940-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_559ec3960c545c6b9f01db728ad39dba |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1997-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6931cf9cd18a42ed935ec47409e905bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5832ccd1adea2d641edce89ab045446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61144346503366f417b95119870129ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51373e128155efa1f81c3bd86c9a0fb3 |
| publicationDate | 1999-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2328940-A |
| titleOfInvention | Preparation of Benzodiazapine-3-alkylcarboxylate |
| abstract | A process for preparing benzodiazepine-3-alkyl carboxylate of formula (I) and its pharmaceutically acceptable salts and esters wherein R<1> is methyl, ethyl or isopropyl ; R<2> and R<3> are each independently hydrogen or C1-C6 lower alkyl ; R<4> is hydrogen, halogen or trifluoromethyl ; carbon atom denoted as c has the S-or R, S- configuration, comprising the steps of: i) preparing the compound of formula(VI) by treating compound of formula (V) with an alkyl amine in an inert organic solvent; ii) preparing the compound of formula(VIII) by addition of halogenating agent to compound of formula (VI) ; and iii) cyclization of compound of formula(VIII) in the presence of base to form the compound of formula(I). Compounds of Formula (V) are also claimed. |
| priorityDate | 1997-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.