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filingDate 1996-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1998-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2318577-A
titleOfInvention Solvent dried polysaccharide sponge
abstract A method of preparing water-insoluble polysaccharide sponges comprises (a) providing an aqueous solution of a soluble polysaccharide; (b) freezing the solution; (c) treating the frozen solution with a water-miscible organic solvent such as isopropanol to effect solvent exchange for the water in the frozen solution; and (d) drying the resulting polysaccharide material. The organic solvent contains a cross-linking agent such as calcium chloride to render the polysaccharide water-insoluble in the solvent-exchange step (c). The resulting materials are more conformable and less friable than freeze-dried polysaccharide sponges.
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