http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2306471-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-81 |
| filingDate | 1996-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9771e55f6fda3bf3610b82a6e087154e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c72063c0b7ccf109cf1d35342af33d2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b2c8880ec9bd65f7864aa77b2f0f0e9 |
| publicationDate | 1997-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2306471-A |
| titleOfInvention | Methanesulfonate salts of antipsychotic benzofuran derivatives |
| abstract | The methanesulfonate salt of a class of antipsychotic compounds of formula (I) comprises a benzo[b]furan moiety and a substituted heterocyclic moiety, linked via the 3-position of the benzo[b]furan moiety by a methylene group. A represents hydrogen, C 1-6 alkyl, C 1-6 alkoxy, halogen, cyano or trifluoromethyl; ```Q represents a heterocycle as defined in claim 1; and R 3 , R 4 , R 5 are hydrogen or a substituent as defined in claim 1. These compounds are antagonists of dopamine receptor subtypes within the brain, being extremely potent antagonists of the human dopamine D 4 receptor subtype and have a selective affinity for the D 4 subtype over other dopamine receptor subtypes, possess advantageous qualities in terms of their improved aqueous solubility relative to the corresponding free base and, as such, provide for greater ease of formulation and display enhanced pharmacokinetic properties, including oral absorption. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03080055-A1 |
| priorityDate | 1995-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.