http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2281294-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 |
filingDate | 1993-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef3fca81aecb66bf8abcb6f30dff0cf8 |
publicationDate | 1995-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-2281294-A |
titleOfInvention | Process for producing half esters of the macrolide FK506 |
abstract | Half esters of the compound FK506 with dicarboxylic acids are produced bv reacting a mixture comprising FK506 and a dicarboxylic acid or anhydride thereof, such as succinic anhydride, in the presence of a dialkylaminopyridine such as 4-dimethylaminopyridine, in the absence of other bases. The FK506 half esters thus produced are useful as intermediates in the preparation of various conjugates for utilization in diagnostic assays for the compound FK506. The succinate ester has the formula:- <IMAGE> |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005105812-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7625726-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7445916-B2 |
priorityDate | 1993-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.