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filingDate 1994-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d565a742d637ef9ea93210626fb897d0
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publicationDate 1994-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2279073-A
titleOfInvention 1-beta-methyl-2-thiolic carbapenem derivatives
abstract The present invention provides new 1- beta -methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and method for the preparation thereof, <IMAGE> where R<1> and R<2> are defined herein. Compounds of the invention are very stable against DHP-1 enzyme due to effective shielding of the carbapenem ring structurally and are highly effective against both gram-positive and gram-negative microorganisms, especially having a remarkable effect on Pseudomonas aeruginosa known to be a strongly resistant disease organism.
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priorityDate 1993-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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