Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5d79e4f64a4b8eba54e0e1a86b09dca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_559ec3960c545c6b9f01db728ad39dba |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate |
1994-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d565a742d637ef9ea93210626fb897d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf2e39fdeb72e3ceeb4858412b3685d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3604466e1b223ea54b109db37821303 |
publicationDate |
1994-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
GB-2279073-A |
titleOfInvention |
1-beta-methyl-2-thiolic carbapenem derivatives |
abstract |
The present invention provides new 1- beta -methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and method for the preparation thereof, <IMAGE> where R<1> and R<2> are defined herein. Compounds of the invention are very stable against DHP-1 enzyme due to effective shielding of the carbapenem ring structurally and are highly effective against both gram-positive and gram-negative microorganisms, especially having a remarkable effect on Pseudomonas aeruginosa known to be a strongly resistant disease organism. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101260108-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6090802-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0882728-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0882728-A4 |
priorityDate |
1993-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |