http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2276168-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5deddb47ccaab1d4da2aacc344dd8717 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4816 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-32 |
| filingDate | 1992-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fb335e0cff8c02dc5db7abe7a61ad28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a69579b22276875e6ebc664b3bca720 |
| publicationDate | 1994-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2276168-A |
| titleOfInvention | Amine derivatives containing a phosphonic,phosphonous or phosphinic acid moiety |
| abstract | This invention concerns compounds of formula (I) wherein E represents hydrogen, C1-C6 alkyl or a group Ar<1>-A<1>-; Ar and Ar<1> when present each represent an aryl group of 6 to 10 carbon atoms or a heteroaryl group of 5 to 10 ring atoms, which are optionally substituted by one or more substituents selected from alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, halogen, haloalky of 1 to 6 carbon atoms, haloalkoxy of 1 to 6 carbon atoms, cyano, amino, mono- or di-(C1-C6) alkylamino, hydroxy and nitro; A and A<1> when present are the same or different alkylene groups having one or two carbons linking Ar or Ar<1> to N, each optionally substituted by alkyl of 1 to 6 carbon atoms and/or an optionally substituted Ar group as defined above. B is a straight chain alkylene group of 3 or 4 carbon atoms optionally substituted by alkyl of 1 to 6 carbon atoms, and D represents P(O)(OR<1>)(OR<2>), P(O)(H)(OH) or P(O)(R<3>)(OR<4>) where R<1> and R<2> are independently hydrogen, alkyl of 1 to 6 carbon atoms or alkyl of 7 to 12 carbon atoms; R<3> is -CH(Oalkyl)<2> in which the alkyl group contains 1 to 6 carbon atoms and R<4> is alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 12 carbon atoms which compounds are GABA autoreceptor agonists useful as antidepressants and for treating senile dementia. <IMAGE> |
| priorityDate | 1991-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.