| abstract |
Compounds of the general formula (I):- <IMAGE> and salts and solvates (eg hydrates) thereof, in which R<1> represents H, F, Cl, Br, I, C1-6alkyl or C1-6alkoxy; R<2> represents an optionally substituted phenyl or pyridyl group; R<3> represents the group <IMAGE> (where R<11> is H or C1-6alkyl); and R<3> and R<4> are optional standard substituents; are useful in the treatment of depression and other CNS disorders, being 5-HT1D antagonists. |