| abstract |
There are disclosed functional epitopes which are purified from human HSP 90 or which are synthesised to correspond to such purified epitopes, which are, if purified, unchanged or changed by substitution of selected amino acids and if synthesised are identical to the purified epitopes or differ from the purified epitopes by substitution of selected amino acids, and which cross-react with an antibody raised against a stress protein. The stress protein may comprise a fungal stress protein e.g. Candida 92 and/or 47 kD; Aspergillus 40, 51 and/or 88/84 kD, Pneumocystis carnii proteins or a bacterial stress protein e.g. Streptoccal 90 kD; Coryneform 86 and/or 52 kD stress proteins. |