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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-22
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-22
filingDate 1992-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd9fd6f4df81a0ce729dd206bdd61435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c33c0af94289b80b51ffe813d240daa5
publicationDate 1993-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2262097-A
titleOfInvention Manufacture of 4H-3,1-benzoxazin-4-ones
abstract A process for the manufacture of 4H-3,1-benzoxazin4-ones of the general formula I <IMAGE> in which R<1> denotes hydrogen, C1-C4 alkyl, C1-C4 alkoxy, carboxyl, sulfo, nitro, or halogen, R<2> denotes C1-C20 alkyl, phenyl, or phenylalkyl having from 1 to 4 carbon atoms in the alkyl group, in which a phenyl nucleus, if present, can be substituted by up to two C1-C4 alkyl groups, C1-C3 haloalkyl groups, C1-C4 alkoxy groups, C1-C3 haloalkoxy groups, C1-C4 alkylmercapto groups, C1-C3 haloalkylmercapto groups, carboxyl groups, sulfo groups, C1-C4 alkylsulfonyl groups, C1-C3 haloalkylsulfonyl groups, nitro groups, or halogen atoms and n is equal to 1 or 2, by the reaction of anthranilic acid or an anthranilic acid derivative of the general formula II <IMAGE> with an acyl halide of the general formula III <IMAGE> in which X denotes chlorine or bromine and R<1>, R<2> and n are as defined above, wherein the anthranilic acid II is reacted with an approximately stoichiometric amount of the acyl halide III, without the addition of a base, in an organic solvent at a temperature of from 60 DEG to 200 DEG C, after which the N-acyl anthranilic acid formed as intermediate is cyclized in known manner in situ.
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priorityDate 1991-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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