http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2260134-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b9f373878f16dc291ff597162e9b344 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 |
| filingDate | 1991-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55e1c01975601cc752ffdf6ee3da1165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2625f59741b745375eee5ecf5ac8ad02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d14fcddbb59ff4a204f7b1fa76483881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24f17fd67e59ce02396c55fee5f1647c |
| publicationDate | 1993-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2260134-A |
| titleOfInvention | Derivatives of poly-5-amino-3-carboxy-1-methyl compounds |
| abstract | Compounds of the formula (I> <IMAGE> wherein W is =O, =S or =N-H, m and n are 1 to 4. B and B1 are a) -(CH2)p-NR1R2 wherein p is 2 to 4 and R1 and R2 @are H or C1-C6 alkyl; b) wherein q is 1 to 4, R3 is H and R4 and R5 @are H or C1-C6 alkyl; @or R3 and R4 taken together form -CH=CH-, CH2CH2- or -CH2CH2CH2- and R5 is H or C1-C6 alkyl; c) a saturated or unsaturated carbocyclic or condensed carbocyclic ring substituted by one to three basic groups; d) a saturated or unsaturated heteromonocyclic or heterobicyclic ring containing 1 to 3 O, N or S atoms and substituted by 1 to 3 @basic groups; e) a saturated or unsaturated carbocyclic or condensed carbocyclic ring containing 1 to 3 acid groups; f) a saturated or unsaturated heteromonocyclic or heterobicyclic ring containing 1 to 3 O, N or S atoms and substituted by 1 or @more acid groups; g) a pyranyl of furanyl sugar residue substituted by 1 too 3 acid groups; or h) -CH2(CHA)rCH2A wherein each A is an acid group and r is 0 to 2, and the pharmaceutically acceptable @salts thereof have activity as antiogenesis inhibitors and are useful in particular in cancer therapy, administered either alone or together with an antitumour agent. Precursors of the above compounds have the formula:- <IMAGE> or are acid addition salts thereof.r |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3381897-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2310207-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6426067-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018177863-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9803573-A1 |
| priorityDate | 1991-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.