abstract |
A chimaeric protein is provided, capable of forming part of a capsid assembly and comprising the amino acid sequence of the coat protein of phage MS-2, or a conservatively modified variant thereof, or sufficient of said sequence or variant to retain the capability of forming a capsid assembly, which amino acid sequence has been modified by removal of the cysteine residues present externally of the N-terminal protuberant beta -hairpin of the coat protein and insertion of a cysteine residue within the region corresponding to the N-terminal protuberant beta -hairpin. |