Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac40ffdd0f9b7563bab9d5dccaa8a6b3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-42 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate |
1991-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fcee3941a8790d0ad9002d3e4b03cb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd18704173437b4def6adc2094fb86f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dfbe293c35babe38952642ce3af1e8 |
publicationDate |
1992-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
GB-2246780-A |
titleOfInvention |
Antibody reagents specific for IgA- alpha 1 antitrypsin complex indicative of rheumatoid arthritis |
abstract |
The assay of rheumatoid arthritis by reference to IgA- alpha 1 antitrypsin complex present in analytes is facilitated by ligands comprising an antibody domain specific for an antigenic determinant of a complex of human IgA and alpha 1-antitrypsin, said antibody domain being substantially non reactive with free human IgA and free human alpha 1-antitrypsin. The ligands may be monoclonal antibodies to the naturally occurring IgA- alpha 1AT complex. Alternatively monoclonal or polyclonal antibodies to a synthetic peptide, preferably including an amino acid sequence: Val-Ser-Val-Val-Met-Ala-Glu-Val-Asp-Gly-Thr-Cvs-Tyr linked by cysteine bridge to the amino acid sequence. Gly-Met-Phe- Asn-Ile-Gin-His-Cys-Lys-Lys-Leu-Ser-Ser are IgA- alpha AT specific. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5601821-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2261665-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2261665-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5955076-A |
priorityDate |
1990-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |