http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2219938-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 1989-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dd4533fb55e381d9cdd8182a48e3683 |
| publicationDate | 1989-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2219938-A |
| titleOfInvention | Use of a thromboxane receptor antagonist in pregnancy-induced hypertension |
| abstract | The use of a compound of formula (1> <IMAGE> wherein R<1> is a H or methyl; X is cis or trans -CH=CH- or -CH2CH2-, m is 2, 3 or 4 and n is 1; or X is trans -CH=CH-, m is zero and n is 3; Y is a saturated heterocyclic amino group (attached to the cyclopentane ring via the nitrogen atom) which a has 5-8 ring members; Alk is a straight or branched C1-5 alkyl; l is zero or 1; p is zero, 1, 2, 3 or 4; R<2> is OH, -OCOR<3>, -CO2R<3>, -CONR<3>R<4>, -SO2NR<3>R <4, -NHCOR<3>, -NH3, -NHSO2R<5>, -SO2R<5>, -SR<5>, -NR<3>R<4>, -COR<5>, NHCONR<3>R<4> or -NHCSNH2; R<3>, and R<3a>and R<4> are each H or a C1-4 alkyl or C7-10 aralkyl group; and R<5> is a C1-4 alkyl group; or a physiologically acceptable salt, solvate or cyciodextrin complex thereof in the manufacture of medicaments for the therapy or prophylaxis of conditions associated with vasoconstriction and/or platelet aggregation in the uteroplacental circulation and/or excessive synthesis of thromboxane A2 in a pregnant female subject. |
| priorityDate | 1988-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.