| abstract |
A trypanocide drug delivery system comprises a trypanocide dispersed in least one biodegradable polymer. Suitable trypanocides include homidium chloride or bromide, isometamidium, quinpyramine sulphate and diminazine aceturate. The polymer may be polyglycolide, poly-(L-lactide), poly-(D, L-lactide), polycaprolactone, poly-( beta -hydroxy butyrate), poly-( beta - hydroyvalerate) or poly-( alpha -aminoacids). The composition may be administered by intramuscular or subcutaneous injection or by surgical implantation. |