http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2184445-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9433d383d1922b3df0ca6c182c7d3925 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 |
| filingDate | 1986-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49ab7ce4c2c59b8014d90ecdcb0cf547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad010b060a12dc3b961b490359a7765e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5802a8ce284e999cb81942a244ddee86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10aeaca4b4a5fbe70887639aed3a22ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed74c8934b4da083b959936beb9e5696 |
| publicationDate | 1987-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2184445-A |
| titleOfInvention | Optically active 2-chloro-12-(3-dimethylamino-2-methylpropyl)-12H- dibenzo[d,g][1,3,6]dioxazocines and a process for the preparation thereof |
| abstract | Optically active 2-chloro-12-(3-dimethylamino-2-methylpropyl)- 12H-dibenzo-[d,g][1,3,6]dioxazocines of the formulan n<IMAGE>n and pharmaceutically acceptable acid addition salts thereof, are especially active against Parkinson's disease. n<??>The optically active enantiomers are prepared by n n a) resolving the racemic 2-chloro-1 2-(3-dimethylamino-2-methylpropyl)-12H-dibenzo[d,g][1,3,6]- dioxazocine with an optically active organic acid and separating the enantiomers; or n b) dissolving the racemic 2-chloro-1 2-(3-dimethylamino-2-methylpropyl)-12H-dibenzo[d,g]- [1,3,6]dioxazocine in an organic solvent, crystallizing and isolating one of the enantiomers, optionally dissolving additional racemic 2-chloro-1 2-(3-dimethylamino-2-methylpropyl)-12H- dibenzo[d,g][1,3,6]dioxazocine in the mother liqueur obtained and crystallizing and isolating the other enantiomer, and, if desired, repeating the whole process. |
| priorityDate | 1985-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.