http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2166742-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d709e3167fa2f99a1803c9cfeb0aca63 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 |
| filingDate | 1984-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_051b2604142f3bb82721096a58c91465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9cf578a2e104b92796edb32a787dfee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35c5b9930c7a71550f73df674e4ad258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_172b13936f0a881a96df8fd78e5fc8e0 |
| publicationDate | 1986-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2166742-A |
| titleOfInvention | Novel 4-thioandrostene derivatives useful as aromatase inhibitors |
| abstract | 4-Thioandrostene derivatives represented by formula (I): <IMAGE> wherein R1 is hydrogen; C1-C6 alkyl; a C1-C10 aryl or C7-C10 aralkyl group (either unsubstituted or ring substituted by C1-C6 alkyl, halogen, nitro, amino or hydroxy); or C2-C22 carboxylic acyl; R2 is hydrogen; C1-C6 alkyl; a C6-C10 aryl or C7-C10 aralkyl group (either unsubstituted or ring substituted by C1-C6 alkyl, halogen, nitro, amino or hydroxy); halogen; or a group -OR3 wherein R3 is hydrogen, C1-C6 alkyl or C2-C22 carboxylic acyl; or a dimer thereof in which there is no radical R1 as defined above but instead the sulphur atoms attached at the respective 4-positions of two compounds of formula (I) are joined together to form a disulphide linkage; and pharmaceutically acceptable salts of a compound of formula (I), or a said dimer, containing a salifiable group; are aromatase inhibitors useful in the treatment of estrogen-dependent tumors and prostatic hyperplasia. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4988684-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0375559-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2640976-A1 |
| priorityDate | 1984-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.