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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-24
filingDate 1984-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e766886ccc62712cd599b86a23bc556
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd1786f9a2015f5140056f588c1dd800
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publicationDate 1986-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2165535-A
titleOfInvention Carbocyclic compounds
abstract 1) Compounds of the general formula (1> <IMAGE> wherein: n is 1 or 2; W is straight or branched C1-7 alkylene; X is cis or trans -CH=CH-, or -CH2CH2-; Y is a saturated heterocyclic amino group; R<1> is a) optionally substituted phenyl b) C3-6 alkenyl, C3-6 alkynyl, thienylmethyl, furanylmethyl, pyridinyl or C5-7 cycloalkyl (optionally substituted by one or more C1-4 alkyl groups); c) -CH2COR<6> where R<6> is optionally substituted phenyl; d) -(CH2)mB(CH2)nR<3> where m is 1-3, n is 0-3 and B is -O- or -S-, provided that when m is 1 and n is 0 then R<3> is not a hydrogen atom; e) -(CH2)pR<7> wherein p is 2 or 3 and R<7> is an amino group or an acetylamino or benzoylamino group; f> <IMAGE> where R<8> is a hydrogen atom, methyl or phenyl and R<9> is C1-7 alkyl, C5-7 cycloalkyl or phenyl; g) -CH(CO2R<9>)2; h) -CH2OCOR<10> where R<10> is C1-4 alkyl, methoxy or phenyl; i) 1-(acetyloxy)ethyl, (acetyloxy)phenylmethyl, tetrahydro-5-oxo-2-furanyl or tetrahydro-1-oxo-3-furanyl; j) -CH(CH2OH)2; <IMAGE> where R<11> is OH or CH2OH and R<12> is a hydrogen atom, C1-4 alkyl or CH2OH; l) 2,2-dimethyl-1,3-dioxolan-4-yl-methyl R<2> is C1-5 alkyl substituted by phenyl (optionally substituted) thienyl (optionally substituted), naphthyl (optionally substituted) or cinnamyl; and the physiologically acceptable salts thereof. These compounds inhibit good platelet aggregation, bronchoconstriction and vasoconstriction and may be formulated for use as antithrombotic or antiasthmatic agents.
priorityDate 1984-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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