| abstract |
A pharmaceutical composition for administration to the skin comprises a pharmaceutical agent, e.g. benzodiazepine, and a percutaneous carrier liquid comprising: A) a 5-24C aliphatic or cycloaliphatic hydrocarbon which may be halo-substituted, an ester of an alcohol and a 7-18C aliphatic carboxylic acid, a C10-18 mono- or di-ether, and/or a C11-15 ketone; and B) a thiogylercol, lactic acid or ester, cyclic urea, alkyl or acyl urea, alkyl amide and/or pyrrolidone or N-alkyl pyrrolidone. |