| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-465 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62 |
| filingDate |
1984-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_561b4a04b6cb9a2e0fa1aca93474e670
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d7182a6e633779dc414f3e00fd28e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20fbdc7f32959fc7ed12acb0c05affd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d74f3c6495c354e2258996179814d11b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc440654ee79ea5851b9a349563f95ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4ca8b72254e293503ff8e307163fc28 |
| publicationDate |
1984-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
GB-2136424-A |
| titleOfInvention |
Macrolide derivatives |
| abstract |
Novel macrolides of the formula 1: <IMAGE> wherein R is formyl or hydroxymethyl; R<1> is hydrogen or C1-6 alkanoyl; R<2> is hydrogen or <IMAGE> and R<3> is hydrogen or C1-6 alkanoyl; provided that one of R<1> or R<3> must be other than hydrogen; can be prepared by contacting macrocin or lactenocin with an acyl donor in the presence of an acylating enzyme system selected from the produced by Streptomyces thermotolerans ATCC 11416, Streptomyces thermotolerans NRRL 15270 or Streptomyces fungicidicus subsp. espinomyceticus ATCC 21574 and are useful in controlling various pathogenic microorganisms such as mycoplasma species. Enzyme systems from NRRL 15270 are also used to acylate tylosin. |
| priorityDate |
1983-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |