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filingDate 1983-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fbc36cf3237468eb5fc18c209f3418c
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publicationDate 1984-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-2129685-A
titleOfInvention Anti-haemophilic compositions
abstract An intravenous anti-haemophilic pharmaceutical composition contains a mixture of phospholipid and Factor VIII in a ratio of at least 2.5 mu g of phospholipid per international unit of Factor VIII. The phospholipid in the mixture must contain at least 15% of phosphatidyl serine (PS). The composition may be prepared by dispersing PS-rich phoshpolipid in an aqueous solution to afford an emulsion and then incubating the phospholipid emulsion with Factor VIII. Freeze-drying the phospholipid/Factor VIII mixture obtained gives a composition in a form convenient for medical use.
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